What if the mitochondria don't know they're broken? So the mitophagy doesn't occur as it should.
Imagine an old engine and its old carburetor that is no longer tuned correctly. Combustion in the engine still happens. It's the fuel and oxygen ratio that is a bit unbalanced. So it backfires and splutters and puts out a lot of smoke. But it works... Sort of.
What if the mitochondria don't know they're broken? So the mitophagy doesn't occur as it should.
Imagine an old engine and its old carburetor that is no longer tuned correctly. Combustion in the engine still happens. It's the fuel and oxygen ratio that is a bit unbalanced. So it backfires and splutters and puts out a lot of smoke. But it works... Sort of.
What if the mitochondria don't know they're broken? So the mitophagy doesn't occur as it should.
Imagine an old engine and its old carburetor that is no longer tuned correctly. Combustion in the engine still happens. It's the fuel and oxygen ratio that is a bit unbalanced. So it backfires and splutters and puts out a lot of smoke. But it works... Sort of.