PRRARSV – The Furin Cleavage Site: A Nuclear Localization Signal that Translocates the Spike and its mRNA to the Nucleus Inducing H3.3 Histone Deposition and Rapid Aging
PRRARSV – The Furin Cleavage Site: A Nuclear Localization Signal that Translocates the Spike and its mRNA to the Nucleus Inducing H3.3 Histone Deposition and Rapid Aging
This should be connected to methylation because methylation modulates chromatin structure and function, along with gene expression.
Methylation of DNA, ➡️ structural changes via G-quadraplexes which “mold” the DNA methylome.
These G-quadraplexes mark the sites of methylation instability and are associated with Ageing and Cancer.
Essentially, the G-quadraplexes form secondary DNA structures in guanine-rich regions of the genome and these regions are called “ageing clock” sites.
Therefore, the SP could be destabilising the homeostasis of DNA methylation and speeding up the ageing process.
Once again this is connected to Light/UVB, circadian clocks, tryptophan and AhR.
With AhR signalling promoting an age-related tissue degeneration, by inhibiting autophagy, enhancing cellular senescence, and disrupting the extracellular matrix.
I keep asking (myself and others) the same question over and over again, but haven't gotten a viable answer yet: if these jabs were meant to kill, why did 'they' give them to everyone without discernment, randomly, young and old, smart and not so smart people, to them 'useful' and 'unuseful' people. Just makes no sense whatsoever. No logic.
"The biological role of H3.3 has been the subject of intensive recent research. Adding more urgency to this effort, increasing evidence implicates H3.3 and its chaperones in cancer"
"This demonstrates how the Furin Cleavage Site, in a very clever fashion, actually functions not so much to cleave the Spike, but to bring it into the nucleus. There it functions in perhaps its most powerful way to induce rapid aging of the host. "
Even if the bioweapon/ biopharmaceutical doesn't kill you outright, it will accelerate damaging mechanisms in the host.
Imagine the financial boon to the medico-pharmaceutical industry as this plays out....
p.s., can medical practitioners, pharm companies, and any and all entities that forced and/or incentivized the biopharmaceuticals on the populace now be litigated once the eua has been ended?
Do any of you watch Karen Kingston and/or Dr. Ana Milhacea videos? I'm getting information overload but am leaning more towards their theories that it isn't spike but nanotechnology. I'm not nearly as smart as all of these Subtask writers so I tend to go with my gut when I'm trying to make sense of all of this madness. What say you?
Much more sinister mechanism...thanks Walter ...disgusting manmade Bioweapon. Does it help to take cellular optimization products that clears senescent cells?(ie Bio-Fisten) . Thanks again . 🌸🌞🙏
ouch, this research really does concern me on the spike and its malevolence. It really does look designed to kill.
It'd be great to have a "Walter Chestnut for Dummies".
It will kill and increasingly rapidly.
This should be connected to methylation because methylation modulates chromatin structure and function, along with gene expression.
Methylation of DNA, ➡️ structural changes via G-quadraplexes which “mold” the DNA methylome.
These G-quadraplexes mark the sites of methylation instability and are associated with Ageing and Cancer.
Essentially, the G-quadraplexes form secondary DNA structures in guanine-rich regions of the genome and these regions are called “ageing clock” sites.
Therefore, the SP could be destabilising the homeostasis of DNA methylation and speeding up the ageing process.
Once again this is connected to Light/UVB, circadian clocks, tryptophan and AhR.
With AhR signalling promoting an age-related tissue degeneration, by inhibiting autophagy, enhancing cellular senescence, and disrupting the extracellular matrix.
https://twitter.com/teamsforlife/status/1497932520687611906?s=61&t=aqRGjs3ICJ1l1I5DKtLuvQ
https://www.sciencedirect.com/science/article/pii/S1568163723000879
https://pubmed.ncbi.nlm.nih.gov/36140833/
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1221-3
Early on, I referred to this jab as “AGING gene therapy” and told people that you could not pay me a billion dollars to take it!
It’s gene therapy. It ages you. And thanks, Walter for giving this explanation as to why.
Very very smart stuff - meaning created by someone very smart - and yes, evil. I am just listening to Elena Freeland, interviewed by Ala Mihalcea - she's talking about the nana technology being from quite a long time ago. This all fits together so much! The video I'm watching, by the way: https://www.onenewspage.com/video/20230111/15319515/GEOENGINEERED-TRANSHUMANISM-ELANA-FREELAND-AND-ANA-MIHALCEA-MD.htm
Absolutely frightening ... Is this the same for vax produced spike? If so, even more frightening (I'm hoping this is not the case)
I keep asking (myself and others) the same question over and over again, but haven't gotten a viable answer yet: if these jabs were meant to kill, why did 'they' give them to everyone without discernment, randomly, young and old, smart and not so smart people, to them 'useful' and 'unuseful' people. Just makes no sense whatsoever. No logic.
That was a tricky read for me but I get the gist. I'm not sure I want it, but I do get it.
"The biological role of H3.3 has been the subject of intensive recent research. Adding more urgency to this effort, increasing evidence implicates H3.3 and its chaperones in cancer"
"This demonstrates how the Furin Cleavage Site, in a very clever fashion, actually functions not so much to cleave the Spike, but to bring it into the nucleus. There it functions in perhaps its most powerful way to induce rapid aging of the host. "
Even if the bioweapon/ biopharmaceutical doesn't kill you outright, it will accelerate damaging mechanisms in the host.
Imagine the financial boon to the medico-pharmaceutical industry as this plays out....
p.s., can medical practitioners, pharm companies, and any and all entities that forced and/or incentivized the biopharmaceuticals on the populace now be litigated once the eua has been ended?
Maybe that is why they created ek1c4..?
It squeezes the shit out of me, there’s no mistake concerning both squeezing life out of every living thing, not only humans.
Do any of you watch Karen Kingston and/or Dr. Ana Milhacea videos? I'm getting information overload but am leaning more towards their theories that it isn't spike but nanotechnology. I'm not nearly as smart as all of these Subtask writers so I tend to go with my gut when I'm trying to make sense of all of this madness. What say you?
What is know about the duration of this effect? Does it dimmish as the acute infection resolves?
What role does the Graphene play in all of this? It seems that they're goal is also to get GO inside of every human they can.
Much more sinister mechanism...thanks Walter ...disgusting manmade Bioweapon. Does it help to take cellular optimization products that clears senescent cells?(ie Bio-Fisten) . Thanks again . 🌸🌞🙏