Gelsolin is another component of actin binding/clearance. It's secreted by all cells but mostly by muscle, so perhaps muscle atrophy with age reduces gelsolin availability (https://www.jbc.org/article/S0021-9258(18)68469-8/pdf). It is activated by calcium, so maybe higher Vit D levels increase Ca availability, but blood Ca is fairly tightly regulated so maybe not...
Vit C thins the blood and prevents cell death, so it should also help significantly.
Great find, thanks!
Gelsolin is another component of actin binding/clearance. It's secreted by all cells but mostly by muscle, so perhaps muscle atrophy with age reduces gelsolin availability (https://www.jbc.org/article/S0021-9258(18)68469-8/pdf). It is activated by calcium, so maybe higher Vit D levels increase Ca availability, but blood Ca is fairly tightly regulated so maybe not...
Vit C thins the blood and prevents cell death, so it should also help significantly.