Thrilled to hear this Walter . My interest as a gynecologist has been metabolic syndrome and polycystic ovarian syndrome and exacerbation of these syndromes as it pertains to obesity. Thank you.
I had pcos as a teen and thin when first discovered by vag u/s for heavy menses I think.. endo said had no issues and wouldn't have problem getting pregnant as long as I remained thin
They didn't say it was possibly related to metabolic syndrome or any Rx for that
I didn't have issues now in early 50s but I had 2 m/c after first child and they found FVL hetero
I wish ever young girl gets tested for that before she starts the pilll
Because why wait for a clot or Dvt or stroke or m/c to know you carry that gene
Even guys should be screened to know. Smoking increases risk and heparin like injections would be needed for long flights
Prevention worth pound of cure especially for the homozygous folk
Do you guys routinely screen for FVL in young women nowadays?
Mtfhr testing is not the same as FVL testing correct? Or all they all under one big blood test?
Good for you for testing that and doing fam Hx
Hopefully in future these will all be standard test for males and females but I get it's $$
Even with family history though
I was first to know I had FVL in fam from M/c then parents tested and dad found was hetero but luckily never had issues.but good for surgery info etc
with this info too I was able to warn rest of fam n even cousins to check ..
I know our new fam doc didnt want to test 20 yo son for FVL as it wasn't in standard test for that clinic ( think need to go to hospital for that FVL test)🤌
Oh well too bad. we will push for that test cuz good to know for himself .. n his future kids..
Oddly enough my sibling was diagnosed at age 18 with Stein-Leventhal ovarian cysts, which I believe is the same is what is now called PCOS. She was always slender until middle-age. I am unsure if metabolic syndrome is a factor in slender people, but I guess it is possible.
Yes. The good news is it can be treated. Complete recovery and remission after 6 months of acupuncture, anti inflammatory supplements, dietary changes (no wheats, more vegs/herbs, green tea, etc).
Two important factors to include (they do have epi-genetic ramifications):
1) Chronic stress/anxiety/PTSD dysregulates the ANS and that impacts weight (I am convinced that 80-90% of "dis-ease" that one sees in a doctor's office is rooted in life trauma);
2) Contaminated foods (Bisphenol A, atrazine, glyphophosphates, seed oils, and on and on)
Obesity definitely seems to be a very complicated condition. I personally err on the side of recognizing the roll diet plays but I do not think it’s easy to fix with diet. I suspect the reason that most people are not successful in treating obesity with dietary changes is probably 2 fold. 1. The foods that lead to obesity are highly addictive and 2. Most people don’t actually eat the proper foods to address the issue when they try, or for the length of time necessary. These are both difficult issues to address because they are multi-factorial, including things like social pressure, industrialization of food, capture of health agencies, budgetary concerns etc.
In my research, I personally found that the key to understand obesity is found in understanding the microbiome and its role in metabolism. There is excellent research in this area. One of my favorite books is The Good Gut by the Sonnenburgs. Or, The Hidden Half of Nature: The Microbial Roots of Life and Health.
I suspect obesity is actually the body’s mechanism to deal with two things. Nutritional deficiencies and toxicity. If you aren’t getting enough nutrients, it makes sense that your body would increase its hunger signals. And fat cells can be used to store toxins, which keeps said toxins out of circulation and away from important organs, thus incentivizing the body to send more hunger signals or to lower metabolism and store fat even on restricted calories.
If people cut out two things, sugar (and other highly refined carbohydrates), and processed vegetable oils, I really think obesity would start to decline, especially if those calories are replaced with nutrient rich foods. Many other changes would be necessary for optimal health but those two are huge. If we don’t address those and other dietary problems, it won’t matter if obesity is “solved” because the body will just have to turn to other coping strategies to deal with nutritional deficiency and toxicity, which will lead to other diseases.
Almost every way the body deals with less than ideal circumstances, we refer to as symptoms or disease, but if we ignore why it’s happening, we just shift the disease. Like using statins to reduce cholesterol. Statins don’t address the problem, which is inflammation.
I’m obviously not a professional but these are the elephants in the room when we look at obesity. It’s stunning how quickly this condition is growing in the population.
This is wonderful. It will also have to take into account not only poor food or lifestyle habits but prescription drugs that also cause people to gain ridiculous amounts of weight. There are some meds that people say they gain 20-30 pounds within 12-18 months of being on them, and then they can never get that weight off, those particular pounds that only added on after beginning that particular "therapy".
Sometimes it’s just the water trapped in each cell because you have low magnesium.. the cell flounders because the atp switch requires magnesium to switch potassium with sodium... get it out of sync and the cell stays holding sodium.. and water.., metabolic rate slows fat does not get used as fuel...
OMG, I have low magnesium and taking it does help me feel better, it does help my mood at least. But I didn't know that detail, so thank you! But if I take too much magnesium I have... side effects.
Switch to glycinate best all rounder ... taurate(heart) or threonate (brain)versions .. only need 450mg for men ... 350 mg for women daily ... any not used for out the body as most is stored in tissue and bone.... only 1% in blood serum.
Please try it.. 240 mg is about two thirds of your daily intake .
Also be aware if you have been low you do feel a little strange the first week.. because some of the 300 enzymes lay dormant during low levels and soon switch back on with magnesium therapy…
I have been using for three years… 600 mg a day .. no extra trips to the loo.
Do you mean I should take magnesium glycinate? I'm taking magnesium citrate right now. It's a powder product called Calm so I can take as little as I need. I hear magnesium needs to be in an acidic environment to be better absorbed.
Which ever you take you know when you are low..you get a reaction as the 300 enzymes that were laying dormant switch on… it is possible to absorb magnesium through the skin… so this talk about bioavailability is just spin word by those selling it’s product.. the take home is if you use one that does not trigger a bowel movement then you should be getting something… btw .. it can take up to two years to raise these levels to anywhere they should be… check Dr Carolyn Dean she is probably the best teacher when it comes to Mg… has her own website.
My understanding is citrate is citric… and may not agree with people who are more acidic than alkaline.. if you are having toilet issues it may be more prudent to use glycinate .. it is less likely to cause issues and is equally if not more bioavailable.
Each person is different .. I use threonate for my mind and taurate for my body.. both agree with me… low vitamin D or long term ppi use may cause you to be low on magnesium too.
Somewhat correct. Citric acid is a trivalent acid. Magnesium ties up two of the acid groups but there's still one free carboxylic acid group, so expect some acidity overall. In contrast, threonate should be neutral and taurate should be basic (alkaline) due to the free amino group.
......Walter, as Arthur Firstenberg has [unwittingly?] revealed, I can say with CONFIDENCE now that such widescale DEBILITATING metabolic alterations - ESPECIALLY profound destruction of MICROTUBULES, other organic charge-reconciling regulators - as disease-states LIKE 'obesity', are CAUSED by persistent piezoelectric mutative corruption of VITAL enzymatic proteinaceous ('VIRAL', especially) media; both external (sustained wireless radiation exposures, WORST) and INJECTED (aluminum-compound nanoparticulates) agents......here once more, is a link to 'LaoWhy86's overview of CCP contingencies for ATTACKING them which corrborates it.....https://odysee.com/@laowhy86:e/china%E2%80%99s-nightmarish-new-bio-weapon:9
Walter. So far what is missed is the strongest epigenetic factor: vitamin A toxicity. Grant Genereux and Garrett Smith are the best I have found on the topic proving out great work. nutritiondetective.com
The liver rules our lives and is protecting us from fast death by removing and storing toxins any way possible as fast as it can - leading to slow death. Garrett's skills at helping the liver reverse the carnage are improving by the day. Concise theory and practice laid out on twitter
Further disrupting the omega 6 to 3 ratio. Why I love sardines, mackerel and other seafood- they contain resolvins that can help us counter the stress response:
It’s due to destruction of a healthy microbiome…Americans are saturated in glyphosate, wheat/gluten, lectins, EMF, fluoride/chloramines, vaccines, antibiotics/rx drugs, and countless other chemicals destroying our healthy microbiome and guts…the healthy bacteria have been replaced with unhealthy, pathogenic bacteria, yeasts, and fungi.
No, diets fail because they are bad nutrition. As you can find in Dean Ornish's book "Undo it!," his practice shows that when he prescirbes statins, 50% drop it within 6 months, but when he teaches patients a Whole Foods, Plant-Based diet, he has 80% complieance after one year. The point is it is simply good nutrition, people feel good, and they stay on it once they are used to it. See www.nutritionstudies.org and the book The China Study.
I can't wait to find out what you discover on the obesity front. Given the work of Sabine Hazan on the obliteration of the microbiome and bifidobacteria by vaccines and the changes that happened to people during the pandemic-- stress, sleep, high states of fear and threat-- I think there are likely lots of metabolic switches that got flipped for the worse. And now people are desperate to know what works.
Thrilled to hear this Walter . My interest as a gynecologist has been metabolic syndrome and polycystic ovarian syndrome and exacerbation of these syndromes as it pertains to obesity. Thank you.
Brandon u are a gyno? Cool!
I had pcos as a teen and thin when first discovered by vag u/s for heavy menses I think.. endo said had no issues and wouldn't have problem getting pregnant as long as I remained thin
They didn't say it was possibly related to metabolic syndrome or any Rx for that
I didn't have issues now in early 50s but I had 2 m/c after first child and they found FVL hetero
I wish ever young girl gets tested for that before she starts the pilll
Because why wait for a clot or Dvt or stroke or m/c to know you carry that gene
Even guys should be screened to know. Smoking increases risk and heparin like injections would be needed for long flights
Prevention worth pound of cure especially for the homozygous folk
Do you guys routinely screen for FVL in young women nowadays?
MTFHR , yes I screen but take a detailed family history( maternal/ paternal) . I don’t put anyone on BCP willynilly.
Mtfhr testing is not the same as FVL testing correct? Or all they all under one big blood test?
Good for you for testing that and doing fam Hx
Hopefully in future these will all be standard test for males and females but I get it's $$
Even with family history though
I was first to know I had FVL in fam from M/c then parents tested and dad found was hetero but luckily never had issues.but good for surgery info etc
with this info too I was able to warn rest of fam n even cousins to check ..
I know our new fam doc didnt want to test 20 yo son for FVL as it wasn't in standard test for that clinic ( think need to go to hospital for that FVL test)🤌
Oh well too bad. we will push for that test cuz good to know for himself .. n his future kids..
There are a series of tests for FVL, or anti phospholipid syndrome .. MTFHR is part of workup
Folks need to know , it’s important.
Hey Brandon. From a gyno point of view is there such a thing as healthy obesity? No PCOS, reproductive issues, etc?
https://pubmed.ncbi.nlm.nih.gov/24297192/
Oddly enough my sibling was diagnosed at age 18 with Stein-Leventhal ovarian cysts, which I believe is the same is what is now called PCOS. She was always slender until middle-age. I am unsure if metabolic syndrome is a factor in slender people, but I guess it is possible.
Yes , I have a few slender pcos patients . Many suffer from central obesity .
Yes. The good news is it can be treated. Complete recovery and remission after 6 months of acupuncture, anti inflammatory supplements, dietary changes (no wheats, more vegs/herbs, green tea, etc).
It’s called Skinny Fat.
Two important factors to include (they do have epi-genetic ramifications):
1) Chronic stress/anxiety/PTSD dysregulates the ANS and that impacts weight (I am convinced that 80-90% of "dis-ease" that one sees in a doctor's office is rooted in life trauma);
2) Contaminated foods (Bisphenol A, atrazine, glyphophosphates, seed oils, and on and on)
Appreciate your hard work WMC!
Obesity definitely seems to be a very complicated condition. I personally err on the side of recognizing the roll diet plays but I do not think it’s easy to fix with diet. I suspect the reason that most people are not successful in treating obesity with dietary changes is probably 2 fold. 1. The foods that lead to obesity are highly addictive and 2. Most people don’t actually eat the proper foods to address the issue when they try, or for the length of time necessary. These are both difficult issues to address because they are multi-factorial, including things like social pressure, industrialization of food, capture of health agencies, budgetary concerns etc.
In my research, I personally found that the key to understand obesity is found in understanding the microbiome and its role in metabolism. There is excellent research in this area. One of my favorite books is The Good Gut by the Sonnenburgs. Or, The Hidden Half of Nature: The Microbial Roots of Life and Health.
I suspect obesity is actually the body’s mechanism to deal with two things. Nutritional deficiencies and toxicity. If you aren’t getting enough nutrients, it makes sense that your body would increase its hunger signals. And fat cells can be used to store toxins, which keeps said toxins out of circulation and away from important organs, thus incentivizing the body to send more hunger signals or to lower metabolism and store fat even on restricted calories.
If people cut out two things, sugar (and other highly refined carbohydrates), and processed vegetable oils, I really think obesity would start to decline, especially if those calories are replaced with nutrient rich foods. Many other changes would be necessary for optimal health but those two are huge. If we don’t address those and other dietary problems, it won’t matter if obesity is “solved” because the body will just have to turn to other coping strategies to deal with nutritional deficiency and toxicity, which will lead to other diseases.
Almost every way the body deals with less than ideal circumstances, we refer to as symptoms or disease, but if we ignore why it’s happening, we just shift the disease. Like using statins to reduce cholesterol. Statins don’t address the problem, which is inflammation.
I’m obviously not a professional but these are the elephants in the room when we look at obesity. It’s stunning how quickly this condition is growing in the population.
excellent overview of the elephants. consider the third biggest camoflaged elephant. vitamin A toxicity. take a look at nutritiondetective.com
Garrett Smith and Grant Genereux are on to great work. Twitter gives great threads on @nutridetect
This is wonderful. It will also have to take into account not only poor food or lifestyle habits but prescription drugs that also cause people to gain ridiculous amounts of weight. There are some meds that people say they gain 20-30 pounds within 12-18 months of being on them, and then they can never get that weight off, those particular pounds that only added on after beginning that particular "therapy".
Sometimes it’s just the water trapped in each cell because you have low magnesium.. the cell flounders because the atp switch requires magnesium to switch potassium with sodium... get it out of sync and the cell stays holding sodium.. and water.., metabolic rate slows fat does not get used as fuel...
OMG, I have low magnesium and taking it does help me feel better, it does help my mood at least. But I didn't know that detail, so thank you! But if I take too much magnesium I have... side effects.
Doctors seem to know so little about nutrition.
Switch to glycinate best all rounder ... taurate(heart) or threonate (brain)versions .. only need 450mg for men ... 350 mg for women daily ... any not used for out the body as most is stored in tissue and bone.... only 1% in blood serum.
Thanks, I have bought a 4-in-1 magnesium supplement.
Hm. I found a 4-in-1 magnesium here. Is this one effective? https://www.amazon.com/gp/slredirect/picassoRedirect.html/ref=pa_sp_atf_aps_sr_pg1_1?ie=UTF8&adId=A05302063ES3E49LKK1QF&qualifier=1683198523&id=8531292591665286&widgetName=sp_atf&url=%2FZentastic-Triple-Magnesium-Relaxation-Absorption%2Fdp%2FB0BC84FL5C%2Fref%3Dsr_1_3_sspa%3Fcrid%3D1D2KYVY29VZ9%26keywords%3Dmagnesium%2Btaurate%26qid%3D1683198523%26sprefix%3Dmagnesium%2Btaurate%252Caps%252C102%26sr%3D8-3-spons%26psc%3D1%26smid%3DA2HUKRE6MI0QD1
240mg total should give me extra bathroom stops.
Please try it.. 240 mg is about two thirds of your daily intake .
Also be aware if you have been low you do feel a little strange the first week.. because some of the 300 enzymes lay dormant during low levels and soon switch back on with magnesium therapy…
I have been using for three years… 600 mg a day .. no extra trips to the loo.
Do you mean I should take magnesium glycinate? I'm taking magnesium citrate right now. It's a powder product called Calm so I can take as little as I need. I hear magnesium needs to be in an acidic environment to be better absorbed.
Which ever you take you know when you are low..you get a reaction as the 300 enzymes that were laying dormant switch on… it is possible to absorb magnesium through the skin… so this talk about bioavailability is just spin word by those selling it’s product.. the take home is if you use one that does not trigger a bowel movement then you should be getting something… btw .. it can take up to two years to raise these levels to anywhere they should be… check Dr Carolyn Dean she is probably the best teacher when it comes to Mg… has her own website.
My understanding is citrate is citric… and may not agree with people who are more acidic than alkaline.. if you are having toilet issues it may be more prudent to use glycinate .. it is less likely to cause issues and is equally if not more bioavailable.
Each person is different .. I use threonate for my mind and taurate for my body.. both agree with me… low vitamin D or long term ppi use may cause you to be low on magnesium too.
Somewhat correct. Citric acid is a trivalent acid. Magnesium ties up two of the acid groups but there's still one free carboxylic acid group, so expect some acidity overall. In contrast, threonate should be neutral and taurate should be basic (alkaline) due to the free amino group.
Thankyou… that was something I did not know.
I’m pretty chubby, not dangerously obese but heftier than I’d like to be. I really look forward to this, sounds very fascinating.
Rich, you may want to look into how much blue light you're exposing yourself to, and ramp up infrared in AM sunlight:
https://romanshapoval.substack.com/p/why-obesity-starts-in-the-eye
The Ethical Skeptic has some good material on this at his site (start with The Worthless Human Lie of the Diet Cartel).
interesting ... however, we want to hear that we can do it!
thanks for all you do!!
......Walter, as Arthur Firstenberg has [unwittingly?] revealed, I can say with CONFIDENCE now that such widescale DEBILITATING metabolic alterations - ESPECIALLY profound destruction of MICROTUBULES, other organic charge-reconciling regulators - as disease-states LIKE 'obesity', are CAUSED by persistent piezoelectric mutative corruption of VITAL enzymatic proteinaceous ('VIRAL', especially) media; both external (sustained wireless radiation exposures, WORST) and INJECTED (aluminum-compound nanoparticulates) agents......here once more, is a link to 'LaoWhy86's overview of CCP contingencies for ATTACKING them which corrborates it.....https://odysee.com/@laowhy86:e/china%E2%80%99s-nightmarish-new-bio-weapon:9
Walter. So far what is missed is the strongest epigenetic factor: vitamin A toxicity. Grant Genereux and Garrett Smith are the best I have found on the topic proving out great work. nutritiondetective.com
https://ggenereux.blog/
The liver rules our lives and is protecting us from fast death by removing and storing toxins any way possible as fast as it can - leading to slow death. Garrett's skills at helping the liver reverse the carnage are improving by the day. Concise theory and practice laid out on twitter
@nutridetect
So many eagerly await your return to this important work, Walter. Thank you. 🙏
Obesity (and most modern ailments) are very likely due to PUFAs
https://robertyoho.substack.com/p/219-mercola-may-have-discovered-the
Further disrupting the omega 6 to 3 ratio. Why I love sardines, mackerel and other seafood- they contain resolvins that can help us counter the stress response:
https://romanshapoval.substack.com/p/the-best-brainfood
It’s due to destruction of a healthy microbiome…Americans are saturated in glyphosate, wheat/gluten, lectins, EMF, fluoride/chloramines, vaccines, antibiotics/rx drugs, and countless other chemicals destroying our healthy microbiome and guts…the healthy bacteria have been replaced with unhealthy, pathogenic bacteria, yeasts, and fungi.
Blue light and EMF are a huge factor as they affect the POMC pathway:
https://romanshapoval.substack.com/p/why-obesity-starts-in-the-eye
Thank you for your work Walter.
No, diets fail because they are bad nutrition. As you can find in Dean Ornish's book "Undo it!," his practice shows that when he prescirbes statins, 50% drop it within 6 months, but when he teaches patients a Whole Foods, Plant-Based diet, he has 80% complieance after one year. The point is it is simply good nutrition, people feel good, and they stay on it once they are used to it. See www.nutritionstudies.org and the book The China Study.
I can't wait to find out what you discover on the obesity front. Given the work of Sabine Hazan on the obliteration of the microbiome and bifidobacteria by vaccines and the changes that happened to people during the pandemic-- stress, sleep, high states of fear and threat-- I think there are likely lots of metabolic switches that got flipped for the worse. And now people are desperate to know what works.