SOLVED: SPED (SPIKE PROTEIN ENDOTHELIAL DISEASE) AND SUDDEN DEATHS: ‘DEAD IN BED’ SYNDROME: THE DAMAGED ENDOTHELIUM CAUSING SYMPATHETIC OVERACTIVITY

Lessons from the rapidly deceased youth in the current Japanese COVID wave

Although the Autonomic Nervous System may impact on vascular function, the reverse may also be true.

The Relationship between Vascular Function and the Autonomic Nervous System
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072858/

In the current wave of COVID infections in Japan, a disturbing pattern has emerged. Young people with no comorbidities have been dying, often within a week from the onset of symptoms. However, THEY HAVE NOT BEEN EXPERIENCING RESPIRATORY DISTRESS. Instead, the presenting symptoms have been IMPAIRED CONSCIOUSNESS, VOMITING AND CONVULSION.

Researchers at the institute closely examined 29 deaths. By age, eight were under 12 months old, six were aged from one through four. Twelve others were aged from five through 11, and three were aged from 12 through 19. Among them, 15, or about half, had no underlying health issues.

Of the 15 who were eligible for vaccinations, two had been vaccinated twice.

When they were brought to medical institutions, 79 percent had fever, 52 percent complained of nausea and vomiting, and 45 percent had impaired consciousness. Impaired consciousness, vomiting and convulsion were the most common symptoms among those without underlying health problems. The researchers said that for this reason, it is important to watch for non-respiratory symptoms as well.

Survey: Half of under-20 victims of COVID-19 had no underlying conditions
https://www3.nhk.or.jp/nhkworld/en/news/20220915_06/

Yet, how can such seemingly innocuous symptoms be a harbinger for rapid and/or sudden death? BECAUSE THEY HAPPEN TO BE SYMPTOMS OF AUTONOMIC DYSFUNCTION!

Autonomic symptoms and signs rarely occur as isolated phenomena without impaired consciousness. Ictal nausea with vomiting is a rare clinical manifestation of seizures. Ictal vomiting is considered a localizing sign in patients with partial seizures of temporal origin. We encountered two patients with simple partial seizures that produced nausea with vomiting as the sole symptom, and we describe the interictal electroencephalographic and magnetoencephalographic findings.

Ictal nausea with vomiting as the major symptom of simple partial seizures: electroencephalographic and magnetoencephalographic analysis
https://pubmed.ncbi.nlm.nih.gov/18054131/

Once again, we understand why those with Diabetes are more at risk for death from COVID its Spike Protein.

We conclude that the 'dead in bed' syndrome probably occurs in Type 1 diabetic persons with early autonomic neuropathy, resulting in relative sympathetic overactivity. Ventricular dysrhythmias may occur in the context of early autonomic neuropathy, with relative sympathetic overactivity, in young Type 1 diabetic persons.

Is undetected autonomic dysfunction responsible for sudden death in Type 1 diabetes mellitus? The 'dead in bed' syndrome revisited
https://pubmed.ncbi.nlm.nih.gov/10477206/

Now we can fully understand how the assault on the microvascular ENDOTHELIUM is causing the DYSFUNCTION OF THE CHOLINERGIC ANTI-INFLAMMATORY REFLEX, additionally explaining why the aged are at substantial risk.

This review focuses on the mechanisms underlying age-related alternations in the ANS and how an imbalance in the ANS, evaluated by MSNA and heart rate variability (HRV), potentially facilitates inflammation when the homeostatic mechanisms between reflex neural circuits and the immune system are compromised, particularly the dysfunction of the cholinergic anti-inflammatory reflex.

The role of age-associated autonomic dysfunction in inflammation and endothelial dysfunction
https://link.springer.com/article/10.1007/s11357-022-00616-1

Also, this explains why those with MENTAL HEALTH CONDITIONS have been especially susceptible to severe and fatal COVID – AS WELL AS LONG COVID!

Possibly via a similar mechanism, acute mental stress may contribute to cardiovascular disease progression via ANS effects on the endothelium. Anxiety has also been shown to be associated with endothelial dysfunction via autonomic dysregulation, evaluated by spectral analysis of heart rate variability in 41 subjects.

The Relationship between Vascular Function and the Autonomic Nervous System
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072858/

INDEED! ON SEPTEMBER 14th THIS WAS PROVEN TO BE TRUE!

Depression, anxiety, worry about COVID-19, stress and loneliness were all associated with an increased risk (32% - 46%) for Long COVID. Those who had two or more types of mental distress prior to infection were at nearly 50% increased risk for post-COVID-19 conditions.

Mental health conditions raise risk of Long COVID
https://www.gavi.org/vaccineswork/mental-health-conditions-raises-risk-long-covid#

My major concern? Are reinfections/exposures to SARS-CoV-2 incrementally advancing  a mechanism by which individuals ever increasingly become obituaries lamenting that they “DIED SUDDENLY?”

I urge all to read the following EXTREMELY IMPORTANT PAPER:

The Relationship between Vascular Function and the Autonomic Nervous System
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072858/