SEVERE COVID, LONG COVID AND SPIKE-PROTEIN INDUCED SYSTEMIC AMYLOIDOSIS AS AN AUTOCATALYTIC REACTION: IT IS NOT A QUESTION OF AMYLOID OR PRION, IT IS DEPENDENT ON THE RATE OF PROTEIN AUTOCATALYSIS AND
SEVERE COVID, LONG COVID AND SPIKE-PROTEIN INDUCED SYSTEMIC AMYLOIDOSIS AS AN AUTOCATALYTIC REACTION: IT IS NOT A QUESTION OF AMYLOID OR PRION, IT IS DEPENDENT ON THE RATE OF PROTEIN AUTOCATALYSIS AND
“Misfolded PrP was amplified by rounds of sonication…” Sonification - really. Now that’s interesting. Based on the way it’s referred to in the excerpt, I gather it’s a standard technique in this sort of research.
I find it particularly interesting in relation to the accelerating blanketing of our planet with radio waves/EMFs. The energy of which I assume have sound components outside the audible spectrum.
What's the mechanism for saunas? I've got an authentic Finnish sauna I build years ago but have fallen out of the habit. Need to restart it I think.
Anyone else have any experience with Lithospermum erythrorhizon (gromwell root powder)? It's a 3CL protease inhibitor along with a bunch of other very interesting potential anti-clotting properties. Pretty good write-up on it here along with links to some papers:
Please expand on your definition of intermittent fasting. As a long-time practitioner of IM I know many people use the term but mean different things... Thanks.
Unfortunately, it is not only the vaxxed who are potential victims. You can get 'spiked' by the virus itself, although from what I understand, typically with a smaller dose.
needs biopsy of the particular organ which is effected, and could be any in your body. that is why you hear all the time nowdays, that doctors cant find anything wrong with the tests and dont understand whats going on but the patient seems to be losing weight etc. etc.
In Sweden they are using low level laser therapy and also infrared light therapy to slow and/or reverse the amyloids. Also, Danish biotechnology firm QuantBioRes is testing deactivation mechanism for Covid. They have been using Resonant Recognition Model (RRM) technology to predict bioactive mutations and electromagnetic frequency, among other markers, and study protein activity with the goal to produce treatments for resistant bacteria and viral diseases. What they are finding could be used in reversing dementia like processes. How do I know all this? I tried everything I could to help my mum when she was diagnosed with dementia. We visited so many research centres, universities, neurologist, nutritionists etc and tried everything we were told…
I can not help but wonder, what would happen if Walter and all the other brilliant scientist active here on substack and Twitter were to join their brain power to find some sort of cure for Covid/Dementia? What would need to happen to get you all on board? What is the amount of $$$ that would make that possible? Who would you like to be a Project Lead? How would you like to work with? What would you need to happen to collaborate? What is stopping you? What would be one thing that would motivate you to join your brain power and work together on cure for Covid/Dementia?
Your work has synergies with research that is going on at University of Tasmania
I am not sure what is the best way to connect so I am sharing their details. James is the admin officer there, Professor James Vickers is a Director and both would be happy to engage with you and/or look into possible co-research projects
Your article rightfully labels the vaxxines as a primary mechanism for the development of amyloids, but it seems Walter is expanding the warning to anybody that has contracted COVID2. Clearly nobody should be taking the vaxx, but are the outcomes you reference inevitable for the unvaxxed as well?
Short answer, IMO have some concern based on how sick you were, how many times and how well you recovered.
No one knows how much is too much and surely it would vary by individual as some are likely better at clearing while others the speed of the autocatalytic is too much. Just as some who are infected by the virus still have spike bits in their poop 200 days later and some clear much sooner it's going to be an individual thing.
I think knowing how relatively bad, by spike type, would require a deep dive into the molecular structure of the different spikes.
The "natural" spike from the virus folds to bind and inject. All the engineered spikes are different from the original and differer from each other for IP purposes. They have been "stiffened" to prevent binding to the ACE2 and perhaps this is an inherent mis-fold. I read that Pfiezer was testing 3 versions with 3 different substitutions. I also read that the engineered are mirror image of the original. Every structural change from the original will have an impact on bioactivity.
The easy way is to look at the research and see what has been reported from natural infection vs vax. Natural has caused brain fog, loss of taste and smell, that appear recoverable. Also Lewy bodies in a monkey study but no mad cow. Probably you also have to think about telemeres (vitamin e isomer in walnuts, resveratrol - that's a fun one) and mitocondrion support. There may be more neurological bad news, but one would have to search the research papers. IMO it doesn't hurt to fast, sauna (you can IR and get 2 for one maybe), eat natural anti- amyloid foods (for parkinsons turmeric, farnesol rich foods as one example - rinse and repeat for different amyloid diseases- like heart fermented soybean nattokinase) spend time in the sun without a hat, exercise and so on ( take a shot gun approach). Read. Read side effects and match to your body. These things will help you age well anyway.
Prion we don't know. Conventional wisdom is not favorable but It's so rare let's not rule anything out. Perhaps more are infected and only some go on to develop disease. There were some promising studies about a decade ago involving specific lichens. From this we know that if we put infected sheep brains in a blender with a specifically prepared extraction of "lichen juice" of specific lichens it can get rid of the prion but this is very different from figuring out what in the lichen and how to get it in the right dose to the living infected brain - if such a think can even be done and would even work. Also if it's not too late once symptoms are detected (as it is in Alzheimers at the moment). So there's some hope.
There are some glycine zipper epitopes in the spike protein at the c-terminal end. Look for the GFIAGLIAIVM (L instead of M in SARS1). There are also two GxxxG peptides in the "lower heads" of the spike (GWIFG, GWTAG and GCLIG). This is background https://www.frontiersin.org/articles/10.3389/fnagi.2016.00107/full
Thanks again Walter, brilliant, love you analysis. I’ve always wondered how they will explain away the coming catastrophe. Has a narrative been created that the virus will do this by mutating. I’m just thinking outside the box. Geert has predicted this, but steered clear of criticising the vaccines
Artemisinin absolutely fights C19. Wouldn’t it be interesting if the pathway is by fighting amyloid... I learned about it via Standard Process supplements
The occurrence of hyperactivated platelets and fibrinaloid microclots in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Massimo Nunes, Arneaux Kruger, Amy Proal, Douglas Kell, Etheresia Pretorius
Abstract We have previously demonstrated that platelet poor plasma (PPP) obtained from patients with LongCovid/Post-Acute Sequelae of COVID-19 (PASC) is characterized by a hypercoagulable state reflected in hyperactivated platelets and the presence of considerable numbers of fibrin(ogen) amyloid microclots or fibrinaloid microclots. Due to substantial overlap in symptoms and aetiology between PASC and ME/CFS, we investigated whether coagulopathies, platelet hyperactivation and/or fibrin amyloid formation differed between individuals exhibiting ME/CFS and gender- and age-matched healthy controls. ME/CFS patients were statistically far more hypercoagulable as judged by thromboelastography of both whole blood and platelet-poor plasma. The area of plasma images containing fibrinaloid microclots was commonly more than 10-fold greater in untreated platelet-poor plasma from individuals with ME/CFS than in that of healthy controls.
One of these drugs is tacrolimus. Didn't Adam Gaertner recommend this last year? The others are ninedanib (Ofev), a TKI for lung fibrotic disease, and zotafin, a chemo drug which blocks growth in TKI driven tumers.
What do they have in common? anti- fibrotic or potentially anti-fibrotic?
And didn't Walter Chesnut write about Covid and fibrosis?
The responses had to do with big pharma and how much they would try to make off these drugs. gutwat thinks they may be able to slow it down but isn't sure this is a cure.
My 35 year old niece appears to have developed POTS. Could this be amyloid/spike protein related? She got 2 Pfizer shots and may have had covid subsequently. Her life is over if we can't fix this. Thanks.
My 38yr old cousin, too. Incredibly her consultant here in the UK has admitted it was the Moderna booster dose. Same thing has happened to our 17yr old professional footballer friend. His career is over. They both have medics trying to help them recover their health, but not much progress so far.
“Misfolded PrP was amplified by rounds of sonication…” Sonification - really. Now that’s interesting. Based on the way it’s referred to in the excerpt, I gather it’s a standard technique in this sort of research.
I find it particularly interesting in relation to the accelerating blanketing of our planet with radio waves/EMFs. The energy of which I assume have sound components outside the audible spectrum.
Yes, sonication is what we do to break stuff up. It's fun.
spread the seed
Yeah, if you use a radio receiver you can hear sounds.
Is there a lab test that one could order, or do, that would answer a question whether one is affected by the amyloids described? Thanks
Testing aside, lumbrokinase, saunas, and intermittent fasting all contribute to the destruction of amyloid.
What's the mechanism for saunas? I've got an authentic Finnish sauna I build years ago but have fallen out of the habit. Need to restart it I think.
Anyone else have any experience with Lithospermum erythrorhizon (gromwell root powder)? It's a 3CL protease inhibitor along with a bunch of other very interesting potential anti-clotting properties. Pretty good write-up on it here along with links to some papers:
https://getbetterwellness.com/tollovid/
I bought some of the root powder and am going to experiment with a tea.
Please expand on your definition of intermittent fasting. As a long-time practitioner of IM I know many people use the term but mean different things... Thanks.
Great Igor !!
Play OFFENSE !
Until we can rapidly test the Vaxxed in real time to show the damage and their impending fate, safe and effective" rules the day.
This approach will force the Medical Cabal out of their money grab deliberate death promotion.
And the MSM also.
Unfortunately, it is not only the vaxxed who are potential victims. You can get 'spiked' by the virus itself, although from what I understand, typically with a smaller dose.
https://europepmc.org/article/PPR/PPR518213
my guess is autopsies would be it.
Maybe something can be seen under the microscope?
But what cells or tissues need to be watched and with what stain?
needs biopsy of the particular organ which is effected, and could be any in your body. that is why you hear all the time nowdays, that doctors cant find anything wrong with the tests and dont understand whats going on but the patient seems to be losing weight etc. etc.
Which organs might be the most affected?
And how to make sampling not so invasive for the patient?
Maybe something can be seen under the microscope in blood, or other not so invasive sample?
Lumbrokinase nattokinase
Great insights Walter.
In Sweden they are using low level laser therapy and also infrared light therapy to slow and/or reverse the amyloids. Also, Danish biotechnology firm QuantBioRes is testing deactivation mechanism for Covid. They have been using Resonant Recognition Model (RRM) technology to predict bioactive mutations and electromagnetic frequency, among other markers, and study protein activity with the goal to produce treatments for resistant bacteria and viral diseases. What they are finding could be used in reversing dementia like processes. How do I know all this? I tried everything I could to help my mum when she was diagnosed with dementia. We visited so many research centres, universities, neurologist, nutritionists etc and tried everything we were told…
I can not help but wonder, what would happen if Walter and all the other brilliant scientist active here on substack and Twitter were to join their brain power to find some sort of cure for Covid/Dementia? What would need to happen to get you all on board? What is the amount of $$$ that would make that possible? Who would you like to be a Project Lead? How would you like to work with? What would you need to happen to collaborate? What is stopping you? What would be one thing that would motivate you to join your brain power and work together on cure for Covid/Dementia?
a good way to access infrared light therapy is via NovoThor if one is nearby.
https://www.novothor.com/locations/
Contraindication for people who had any form/stage of cancer ever. Even if considered "cured" 7 years +
thank you Bibi, had not run across that.
Enquiring minds want to know!
Dear Walter
Your work has synergies with research that is going on at University of Tasmania
I am not sure what is the best way to connect so I am sharing their details. James is the admin officer there, Professor James Vickers is a Director and both would be happy to engage with you and/or look into possible co-research projects
dementia.care@utas.edu.au.
James Jestrimski Phone: + 61 3 62266912
Administration Officer
Wicking Dementia Research and Education Centre
University of Tasmania – Private Bag 143, Hobart TAS 7001
utas.edu.au
Horror show.
The death & damage from the DEATHVAX™ continues to pile up...
https://2ndsmartestguyintheworld.substack.com/p/two-new-studies-show-link-between?s=w
Your article rightfully labels the vaxxines as a primary mechanism for the development of amyloids, but it seems Walter is expanding the warning to anybody that has contracted COVID2. Clearly nobody should be taking the vaxx, but are the outcomes you reference inevitable for the unvaxxed as well?
Short answer, IMO have some concern based on how sick you were, how many times and how well you recovered.
No one knows how much is too much and surely it would vary by individual as some are likely better at clearing while others the speed of the autocatalytic is too much. Just as some who are infected by the virus still have spike bits in their poop 200 days later and some clear much sooner it's going to be an individual thing.
I think knowing how relatively bad, by spike type, would require a deep dive into the molecular structure of the different spikes.
The "natural" spike from the virus folds to bind and inject. All the engineered spikes are different from the original and differer from each other for IP purposes. They have been "stiffened" to prevent binding to the ACE2 and perhaps this is an inherent mis-fold. I read that Pfiezer was testing 3 versions with 3 different substitutions. I also read that the engineered are mirror image of the original. Every structural change from the original will have an impact on bioactivity.
The easy way is to look at the research and see what has been reported from natural infection vs vax. Natural has caused brain fog, loss of taste and smell, that appear recoverable. Also Lewy bodies in a monkey study but no mad cow. Probably you also have to think about telemeres (vitamin e isomer in walnuts, resveratrol - that's a fun one) and mitocondrion support. There may be more neurological bad news, but one would have to search the research papers. IMO it doesn't hurt to fast, sauna (you can IR and get 2 for one maybe), eat natural anti- amyloid foods (for parkinsons turmeric, farnesol rich foods as one example - rinse and repeat for different amyloid diseases- like heart fermented soybean nattokinase) spend time in the sun without a hat, exercise and so on ( take a shot gun approach). Read. Read side effects and match to your body. These things will help you age well anyway.
Prion we don't know. Conventional wisdom is not favorable but It's so rare let's not rule anything out. Perhaps more are infected and only some go on to develop disease. There were some promising studies about a decade ago involving specific lichens. From this we know that if we put infected sheep brains in a blender with a specifically prepared extraction of "lichen juice" of specific lichens it can get rid of the prion but this is very different from figuring out what in the lichen and how to get it in the right dose to the living infected brain - if such a think can even be done and would even work. Also if it's not too late once symptoms are detected (as it is in Alzheimers at the moment). So there's some hope.
What do you mean by IR? Thank you!
In sauna context, IR is short for infra-red sauna - a type of sauna which use infra-red lamps for "heat" instead of a conventional sauna stove.
Greetings from a sauna country!
Oh! Yes! That makes sense, ha! Thank you.
There are some glycine zipper epitopes in the spike protein at the c-terminal end. Look for the GFIAGLIAIVM (L instead of M in SARS1). There are also two GxxxG peptides in the "lower heads" of the spike (GWIFG, GWTAG and GCLIG). This is background https://www.frontiersin.org/articles/10.3389/fnagi.2016.00107/full
Thanks again Walter, brilliant, love you analysis. I’ve always wondered how they will explain away the coming catastrophe. Has a narrative been created that the virus will do this by mutating. I’m just thinking outside the box. Geert has predicted this, but steered clear of criticising the vaccines
they’ll claim it’s a mad cow disease from the beef and massively cull the herds as a “solution”.
Wow. Thank you, Igor.
I ran into this paper in this article. Quite a nice breakthrough: https://www.news-medical.net/news/20200506/New-breakthrough-may-help-cure-prion-disease.aspx
And a couple months ago I ran into Artemisinen: https://www.sciencedirect.com/science/article/pii/S221323171730099X?via%3Dihub
Artemisinin absolutely fights C19. Wouldn’t it be interesting if the pathway is by fighting amyloid... I learned about it via Standard Process supplements
Epic so they are reversible.
Lumbrokinase. Therapeutics found!
"Prioloid. Love it!
PREPRINT EXCERPT Fibrinaloid microclots in ME/CFS, too
https://www.researchsquare.com/article/rs-1727226/v1
The occurrence of hyperactivated platelets and fibrinaloid microclots in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Massimo Nunes, Arneaux Kruger, Amy Proal, Douglas Kell, Etheresia Pretorius
Abstract We have previously demonstrated that platelet poor plasma (PPP) obtained from patients with LongCovid/Post-Acute Sequelae of COVID-19 (PASC) is characterized by a hypercoagulable state reflected in hyperactivated platelets and the presence of considerable numbers of fibrin(ogen) amyloid microclots or fibrinaloid microclots. Due to substantial overlap in symptoms and aetiology between PASC and ME/CFS, we investigated whether coagulopathies, platelet hyperactivation and/or fibrin amyloid formation differed between individuals exhibiting ME/CFS and gender- and age-matched healthy controls. ME/CFS patients were statistically far more hypercoagulable as judged by thromboelastography of both whole blood and platelet-poor plasma. The area of plasma images containing fibrinaloid microclots was commonly more than 10-fold greater in untreated platelet-poor plasma from individuals with ME/CFS than in that of healthy controls.
@gutwat1 posted this on twitter the AM. Thought it might interest you. I have her permission to copy to you.
science.org/DOI/10.1126/sciadv.abm2510
One of these drugs is tacrolimus. Didn't Adam Gaertner recommend this last year? The others are ninedanib (Ofev), a TKI for lung fibrotic disease, and zotafin, a chemo drug which blocks growth in TKI driven tumers.
What do they have in common? anti- fibrotic or potentially anti-fibrotic?
And didn't Walter Chesnut write about Covid and fibrosis?
The responses had to do with big pharma and how much they would try to make off these drugs. gutwat thinks they may be able to slow it down but isn't sure this is a cure.
Link is not working...?
https://web.archive.org/web/20220602060637/https://www.science.org/DOI/10.1126/sciadv.abm2510
Wow, 3 drugs I know nothing about and have not yet read mentioned in relation to C19. Interesting! Thank you!
My 35 year old niece appears to have developed POTS. Could this be amyloid/spike protein related? She got 2 Pfizer shots and may have had covid subsequently. Her life is over if we can't fix this. Thanks.
My 38yr old cousin, too. Incredibly her consultant here in the UK has admitted it was the Moderna booster dose. Same thing has happened to our 17yr old professional footballer friend. His career is over. They both have medics trying to help them recover their health, but not much progress so far.
Here in the US nobody admits that the jab has anything to do with it. I hope for my family and yours that we can figure this out.
look into this chlorine dioxide https://andreaskalcker.com/en/
I will, thanks.
Quercetin for amyloids and the prion subclass
Thank you.
Thank you Walter! I guess you’ve already identified this article https://portlandpress.com/biochemj/article/479/4/537/230829/A-central-role-for-amyloid-fibrin-microclots-in