Friday Hope: TEMPOL as a Possible Effective Therapeutic For COVID, Long COVID and Spike Protein Endothelial Disease (SPED)
The Similarities of COVD/Long COVID and SPED to Gadolinium-Associated Systemic Fibrosis
As I am continuing to study the Spike Protein, the more I realize it causes disease of CONSTANT/REPEATED INJURY. And powerful, toxic constant/repeated injury. This is why, I believe, it strongly resembles the effects of third degree burns, radiation and – Gadolinium-Associated Systemic Fibrosis.
Please review the following:
Clinical definition
· rare systemic fibrosing disorder in patients with renal failure that is associated with gadolinium-containing contrast agent
· primarily characterized by
· thickening of skin
· fibrosis of dermis, but can also affect muscle, fascia, lungs, and heart
Pathogenesis
· mechanism is unclear
· gadolinium may dissociate from its chelating molecule and increase the exposure in patients with renal failure
· gadolinium deposition in tissue may cause a tissue injury reaction
· this may activate transforming growth factor TGF-β1 pathway
· gadolinium may also directly increase the number of circulating fibrocytes by stimulating the bone marrow
· increased number of fibrocytes can produce collagen and cause tissue fibrosis
Labs
· ↑ erythrocyte sedimentation rate
· ↑ C-reactive protein
· ↑ ferritin
Gadolinium-Associated Nephrogenic Systemic Fibrosis
https://step2.medbullets.com/renal/121624/gadolinium-associated-nephrogenic-systemic-fibrosis
It would seem that the underlying engine of all things Spike Protein related is REPEATED SEVERE CELLULAR INJURY.
What is most interesting is that TEMPOL seems to attenuate the fibrosis caused by Gadolinium.
When contrast-treated animals were given tempol, the fibrosis and dermal cellularity were greatly attenuated. The same effect was apparent with skin fibronectin quantity: tempol abrogated the contrast-induced increase. Similarly, contrast-induced increases in dermal CD34 and cells expressing α-smooth muscle actin-containing stress fibers were reduced by tempol coadministration.
Pathophysiology of gadolinium-associated systemic fibrosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967166/
And, most surprising?
Just as humans need minerals in their diet, researchers found that SARS-CoV-2 needs clusters of iron and sulfur minerals to replicate in cells. TEMPOL breaks up these clusters and stops the virus from multiplying. This action might prevent severe COVID-19.
Earlier animal and cell culture studies showed that TEMPOL may also reduce COVID-19 symptoms in other ways:
Calming inflammation. SARS-CoV-2 infection sometimes causes an out-of-control immune response called a cytokine storm, which can damage the lungs and other organs and may cause death. TEMPOL may help prevent cytokine storms.
Protecting organs from damage. TEMPOL’s antioxidant activity may protect cells by inactivating free radicals — unstable molecules made by out-of-control immune responses — that can damage organs.
Decreasing clumping of platelets. Platelets are blood cells that help stop bleeding. If they are too sticky and form clumps in blood vessels, as can happen in people with COVID-19, dangerous blood clots can result. TEMPOL may reduce this risk.
TEMPOL: A Potential Home Treatment for COVID-19
https://covid19.nih.gov/news-and-stories/tempol-potential-home-treatment-covid-19
I believe we are very close to understanding COVID/Long COVID and SPED as diseases of constant microinjury caused by the Spike Protein of SARS-CoV-2.
Now we have acetaminophen, Paxlovid, molnupiravir and TEMPOL (1 animal study). But no studies on vitamin D ever sponsored by NIH.
Why would one choose Tempol over SOD (superoxide dismutase) that we already know is safe and that is easy to access. This article is just brings us more distraction that feeds big pharma, the enemy that has created this pandemic and has made billions off of the deaths of humanity both in the creation of this plague and its supposed treatments and preventions. We already know what destroys the spike proteins.. Ivermectin and MMS. MMS cures all of the most difficult cases and anyone who has had covid should do either one of these or both in a series. This article tells you everything you need to know about MMS otherwise known as Chlorine Dioxide and presents videos from the doctor making it famous in Mexico. ENTER THE GREAT AWAKENING WITH THE CURE https://arrowd.substack.com/p/enter-the-great-awakening-with-the