Those with Major Depressive Disorder Already Have a Compromised Endothelium. Escitalopram Mitigates the Damaged Endothelium – Particularly the Microvasculature.
Pandelis, at the beginning of the latest Jeff and Erico video, Jeff mentioned that the three things they have been teaching us about are: The spike protein, mRNA, and IRON. Jeff bade us NOT to take any iron supplements.
I sent them two emails about the mejbcart Substack on iron. ... I bet they read them!
What may be the effective dose and schedule for COVID? I've just had exposure some hours ago to a vaxxed school teacher who coughed all over me. I have fluvoxamine but am going to arrange a prescription for escitalopram.
Methylene Blue has helped me so much with my long Covid issues. It’s the first supplement (if you want to call it that) that I’ve really noticed a big difference with. The brain fog/dizziness is gone. My energy level jumped way up. I still have tinnitus unfortunately, but I can deal with that.
Yes, where did you purchase yours? There are some available on Amazon but I am skeptical of their sources. Also, has anything helped with the tinnitus?
https://cztl.bz/ This place. I started with 2-4 drops, and slowly moved up in the following weeks. Your not supposed to use more than 18 drops or something. Then it’s actually bad for you.
I’d be curious to see the correlation… I wonder if people with anxiety disorders disproportionately went to the murder factories -er… hospitals, when they got COVID symptoms, while all the people I would call normal, just lived life as normal and took chicken soup for it…
To attempt to clarify, while awaiting a possible answer from Walter Chesnut: given the physiological changes described,is there a choice to be made between SSRI and SNRI in order to avoid or to treat Long Covid?
Consider SAD (Seasonal Affective Disorder) which has been characterised (and treated) as a pineal response to inadequate sunlight. Another hypothesis (and therapy) for SAD and depression has been Vitamin D supplementation.
There are many studies of the correlation between Vit. D levels and Covid severity. Dr. Ryan Cole has stated that Vit. D levels above 50 ng/ml are protective.
So, I now look at the correlation between Major Depressive Disorder, endothelial dysfunction, and antidepressant therapy as a marker for Vit. D deficiency.
For some decades I reminded patients that they existed on the "health" of their arterial linings- particularly diabetics, smokers, and those with established coronary artery or vascular disease. Latterly I also suggested that those who manifested SAD use the lights, but also occasionally suggested Vit. D supplementation. Over the past three years I have become very much more aware of the requirement to also assess Vit. D levels, but have not been in clinic.
One of the interesting observations is that endothelial dysfunction is a protean symptom complex. Any vulnerable tissue can be affected and give its typical diagnostic cluster. This is one of the (perhaps intentional) reasons that the spike protein pathology has not been obvious- there are so many manifestations that each one is "only a little bit above normal" that the overall disaster can be dismissed until the total damage is presented.
Walter... Excellent find. Do you think fluvoxamine is similar in effect on microvasc and endothelium?
Thx. It does not appear that fluvoxamine is as effective on the microvasculature. Both should be trialed, though, to determine efficacy.
unfortunately, cant count on trials ... the cavalry is not coming :-)
as always, deepest appreciation for your hard work and determination!!
https://mediaarchives.gsradio.net/rense/special/rense_120922_hr2.mp3
Pandelis, at the beginning of the latest Jeff and Erico video, Jeff mentioned that the three things they have been teaching us about are: The spike protein, mRNA, and IRON. Jeff bade us NOT to take any iron supplements.
I sent them two emails about the mejbcart Substack on iron. ... I bet they read them!
yes, most certainly jeff reads everything and i might add try to take credit when he can :) he is a smart guy. thanks for sharing!
What may be the effective dose and schedule for COVID? I've just had exposure some hours ago to a vaxxed school teacher who coughed all over me. I have fluvoxamine but am going to arrange a prescription for escitalopram.
Yes, it has. I have been writing this for over two years.
Methylene Blue has helped me so much with my long Covid issues. It’s the first supplement (if you want to call it that) that I’ve really noticed a big difference with. The brain fog/dizziness is gone. My energy level jumped way up. I still have tinnitus unfortunately, but I can deal with that.
Yes, where did you purchase yours? There are some available on Amazon but I am skeptical of their sources. Also, has anything helped with the tinnitus?
This is the place to get it - https://cztl.bz/
In Spain, I bought it from amazon.
Interested too.
https://cztl.bz/ This is the place to get it.
Where did you get yours?
https://cztl.bz/ This place. I started with 2-4 drops, and slowly moved up in the following weeks. Your not supposed to use more than 18 drops or something. Then it’s actually bad for you.
I’d be curious to see the correlation… I wonder if people with anxiety disorders disproportionately went to the murder factories -er… hospitals, when they got COVID symptoms, while all the people I would call normal, just lived life as normal and took chicken soup for it…
Chondroitin sulfate protects vascular endothelial cells from toxicities of extracellular histones
https://pubmed.ncbi.nlm.nih.gov/29501579/
Would you hazard a guess as to possible use / utility of SNRI-type antidepressants in treating Long Covid?
The agents act similarly but not the same.
To attempt to clarify, while awaiting a possible answer from Walter Chesnut: given the physiological changes described,is there a choice to be made between SSRI and SNRI in order to avoid or to treat Long Covid?
Lexapro or SPED, Lexapro or SPED, Lexapro or SPED, .... I'm thinking!
Not a big fan of SSRIs.
Me either.
I cannot imagine taking a psychotropic with God knows how many life altering side effects.
Yes, but you can't say that across the board. There are also huge differences.
Look at this from the other point of view.
Consider SAD (Seasonal Affective Disorder) which has been characterised (and treated) as a pineal response to inadequate sunlight. Another hypothesis (and therapy) for SAD and depression has been Vitamin D supplementation.
There are many studies of the correlation between Vit. D levels and Covid severity. Dr. Ryan Cole has stated that Vit. D levels above 50 ng/ml are protective.
So, I now look at the correlation between Major Depressive Disorder, endothelial dysfunction, and antidepressant therapy as a marker for Vit. D deficiency.
For some decades I reminded patients that they existed on the "health" of their arterial linings- particularly diabetics, smokers, and those with established coronary artery or vascular disease. Latterly I also suggested that those who manifested SAD use the lights, but also occasionally suggested Vit. D supplementation. Over the past three years I have become very much more aware of the requirement to also assess Vit. D levels, but have not been in clinic.
One of the interesting observations is that endothelial dysfunction is a protean symptom complex. Any vulnerable tissue can be affected and give its typical diagnostic cluster. This is one of the (perhaps intentional) reasons that the spike protein pathology has not been obvious- there are so many manifestations that each one is "only a little bit above normal" that the overall disaster can be dismissed until the total damage is presented.
Thank you for your work on this subject.
https://pubmed.ncbi.nlm.nih.gov/30081645/