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A STARTLING DISCOVERY: IRON OVERLOAD AND “IRRADIATION” (OXIDATIVE) DAMAGE: THE SPIKE PROTEIN MIMICS MECHANISMS OF THE SPACE ENVIRONMENT

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A STARTLING DISCOVERY: IRON OVERLOAD AND “IRRADIATION” (OXIDATIVE) DAMAGE: THE SPIKE PROTEIN MIMICS MECHANISMS OF THE SPACE ENVIRONMENT

Is the Spike Protein a biodefense research project? A bioweapon? Or both?

Walter M Chesnut
Sep 16, 2022
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A STARTLING DISCOVERY: IRON OVERLOAD AND “IRRADIATION” (OXIDATIVE) DAMAGE: THE SPIKE PROTEIN MIMICS MECHANISMS OF THE SPACE ENVIRONMENT

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To being, please read the caption for the above image:

Hypothetical model on how spaceflight leads to injuries in the musculoskeletal system. Exposure of tissues to the spaceflight environment, such as microgravity and radiation, leads to a decreased mass of red blood cells. This induces elevated iron stores, due to iron release from destroyed erythrocytes. Excess iron leads to an imbalance in redox homeostasis, owing to increased levels of reactive oxygen species (ROS) and reduced levels of antioxidases. The spaceflight environment may also have direct effects on iron metabolism and redox homeostasis. The imbalance of redox status leads to the oxidative damage of cells, which in turn result in injuries in the musculoskeletal system. Other signaling processes are disrupted by the spaceflight environment, and may also cause these defects. Some exogenous iron chelators and antioxidants may block the increases in iron and the imbalance in redox status, thereby preventing oxidative damage.

Effects of Iron Overload and Oxidative Damage on the Musculoskeletal System in the Space Environment: Data from Spaceflights and Ground-Based Simulation Models
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163331/

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This very destruction of red blood cells (RBCs) is caused by or induced by the Spike Protein, creating the EXACT SAME EFFECT.

The spike protein of SARS-CoV-2 has been reported to compete with complement factor H for heparan sulfate binding and amplify the alternative complement pathway on the cell surface. Recent data, however, suggest that BTH after the SARS-CoV-2 vaccination is not due to the direct effect of the spike protein. In this report, it was speculated that increased complement activity due to the inflammatory response after the vaccination was the cause of clinically observed hemolysis.

Hemolysis induced by SARS-CoV-2 mRNA vaccination in patients with paroxysmal nocturnal hemoglobinuria
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169953/

The Spike Protein’s “Irradiation” effects on the endothelium appear to mimic the long term endothelial dysfunction associated with space radiation.

Results from the present study address the question of possible long-lasting interactive effects of simulated weightlessness and space radiation on vascular function. To experimentally address this question, vascular responses of resistance arteries were determined 6–7 months after the cessation of a 14-day hindlimb unloading treatment, a 1 Gy 56Fe irradiation treatment, or a treatment consisting of a combination of the two. Given that the average life-span of male C57BL/6 mice is 878 ± 10 days34, the 6–7 month period represents approximately 23% of animals’ life or roughly the equivalent of 18–20 years in humans. The data show that hindlimb unloading alone had no persistent effect to significantly diminish endothelium-dependent vasodilation, while HZE irradiation alone and in combination with unloading impaired endothelium-dependent vasodilation through the NO signaling mechanism. This decrement in NO signaling appears to be mediated primarily through greater NO scavenging by reactive oxygen species, as evidenced by higher vascular protein content and activity of XO in peripheral and coronary arteries. These data indicate that the long-lasting effects of simulated weightlessness and space radiation on vascular endothelial function are the result of the radiation exposure and are not due to an interaction with weightlessness. As dysfunction of the vascular endothelium is central to the pathogenesis of vascular disease, such adverse arterial effects could lead to the development of occlusive arterial diseases, including myocardial infarction and stroke.

Apollo Lunar Astronauts Show Higher Cardiovascular Disease Mortality: Possible Deep Space Radiation Effects on the Vascular Endothelium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964660/

What makes this hypothesis especially compelling? The interference of space radiation with NO signaling (see quote above), and how NO may be an extremely important therapeutic against the Spike Protein and COVID-19  as they appear to have a parallel effect on NO signaling.

A valid and readily accessible biomarker will be very useful to assess the impact of different interventions on NO signalling, a key player in the pathogenesis of COVID-19.

Nitric oxide in COVID-19: Too little of a good thing?
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00109-8/fulltext

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A STARTLING DISCOVERY: IRON OVERLOAD AND “IRRADIATION” (OXIDATIVE) DAMAGE: THE SPIKE PROTEIN MIMICS MECHANISMS OF THE SPACE ENVIRONMENT

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Jennifer Depew, R.D.
Writes deNutrients - News to Use
Sep 16, 2022Liked by Walter M Chesnut

Bioweapon imo - there is no reason for prion like domains, or snake venom like sequences, or HIV, or any of the other pathogen bits in the chimeric spike if it was meant for benign reasons.

“In immune cells, NF-κB proteins regulate immune cell development, activation, survival, and cytokine production [200], [201]. NF-κB proteins are activated through stimulants such as cytokines, stress, free radicals, ultraviolet radiation,* and infections [200]. They play a central role in regulating immune response to infections. They are highly active in inflammatory diseases and control transcription of many genes involved in immune response and cytokine production [200], [201].” (Sarohan et al, 2021) https://www.sciencedirect.com/science/article/pii/S0898656821002102?via%3Dihub#bb0085

*Hyperinflammation is hyperinflammation for whatever inflammatory reason.

Pomegranate peel promotes Nitric oxide.

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Rob
Sep 16, 2022Liked by Walter M Chesnut

Walter, the reduction in NO was a big clue that we were looking at UVB ionising radiation as -

UVB decreases NO

“UVB light suppresses nitric oxide production”

https://pubmed.ncbi.nlm.nih.gov/12417260/

Whereas, UVA increases NO

https://pubmed.ncbi.nlm.nih.gov/24924758/

UVB also causes Iron overload

“UV irradiation induces the accumulation of lipid peroxides and iron overload in skin damage.”

https://www.sciencedirect.com/science/article/pii/S0925443921002209

And once again the key feature in space was a dysfunction of the mitochondria.

“ Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159838/

NASA looked at using Boron to protect astronauts from the high energy radiation in space, because it is an excellent absorber of secondary neutrons.

https://www.nasa.gov/feature/goddard/real-martians-how-to-protect-astronauts-from-space-radiation-on-mars

Elevated CO2 also increases production of NO and causes vasodilation

https://www.normalbreathing.com/co2-vasodilation/

Ditto Ozone!

https://www.nature.com/articles/s41443-020-0301-1/

Nitric oxide can also be increased by red light, as well as sauna and cold thermogenesis

https://pubmed.ncbi.nlm.nih.gov/34536586/

I doubt it is just a coincidence that Solar Cycle 25 began in December 2019 and the weakening magnetosphere means the earth is now experiencing increasing solar flux/irradiation.

https://www.sciencedirect.com/science/article/abs/pii/S0306987706001824

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