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The Spike Protein Adaptive Immune Response, Free Light Chains and the Induction of Light Chain Amyloidosis
How antibodies created against the Spike Protein may induce systemic amyloidosis.
A very interesting discovery was made when responses to SARS-CoV-2 and its Spike Protein were made regarding Free Light Chains (FLC).
The levels of anti-S-RBD IgG and κFLC were increased in COVID-19 and healthy vaccinated patients when compared to non-vaccinated controls. Elevated levels of FLCs in COVID-19 and healthy vaccinated against SARS-CoV-2 patients, as well as the correlation between free light chains with specific anti-SARS-CoV-2 antibodies and IL-6, reflect hyperactivation of the immune system after contact with coronavirus.
Evaluation of Free Light Chains (FLCs) Synthesis in Response to Exposure to SARS-CoV-2
What I find most significant is that the FLC were HIGHEST in the HEALTHY VACCINATED CONTROLS!
When B Cells create antibodies to invading pathogens, an excess amount of the part of the antibody that attaches to the pathogen is secreted. Excess free light chains can be deposited in tissues causing systemic amyloidosis. I believe we need to screen organs in the general population post COVID and post Spike Protein vaccination to determine if amyloidosis has been induced, and, if so, to what extent the disease is present.
What I find most striking is that symptoms of systemic amyloidosis very strongly resemble Long COVID. And, unless you TEST FOR AMYLOID DEPOSITION, you will not know it is the cause.
Treatment for systemic AL amyloidosis is intended to reduce the excess free light chain load and thereby reverse amyloid deposition.
The not so innocent bystander: an unusual cause of progressive breathlessness
SYMPTOMS OF AL AMYLOIDOSIS INCLUDE:
Shortness of Breath
Unexplained Weight Loss
Loss of Appetite
AL (Light Chain) Amyloidosis: Symptoms, Causes, Treatment, and More
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